Eye Doctors Can Detect Signs of 270+ Health Conditions During Eye Exams

Autoimmune diseases

• Acquired immunodeficiency syndrome
• Antiphospholipid antibody syndrome
• Behçet's disease
• Cicatricial pemphigoid
• Cirrhosis – primary biliary
• Devic disease (neuromyelitis optica)
• Type 1 diabetes
• Lambert-Eaton myasthenic syndrome
• Goodpasture syndrome
• Linear IgA disease
• Melanoma-associated retinopathy
• Mixed connective tissue disease
• Myasthenia gravis
• Pemphigoid
• Pemphigus vulgaris
• Relapsing polychondritis
• Rheumatoid arthritis
• Sarcoidosis
• Scleroderma
• Sjögren’s syndrome
• Systemic lupus erythematosus
• Systemic sclerosis
• Vogt-Koyanagi-Harada disease

Bacterial infections

• Cat scratch fever
• Leprosy (Hansen’s disease)
• Leptospirosis
• Lyme disease
• Rhinosporidiosis
• Syphilis (congenital)
• Tuberculosis
• Tularemia
• Whipple disease

Blood disorders and conditions

• Anemia
• Hyperlipidemia
• Hyperlipoproteinemia
• Hyperlysinemia
• Hypertension (high blood pressure)
• Hyperviscosity syndrome
• Polycythemia rubra vera
• Takayasu arteritis
• Vessel occlusive diseases

Bone diseases and disorders

• Osteoporosis
• Paget's disease

Cancers

• Leukemia
• Lymphoma
• Metastatic disease
• Multiple myeloma (myelomatosis)
• Other cancers
• Pituitary tumors (edemas)
• Waldenström macroglobulinemia

Cardiovascular conditions

• Arteriolosclerosis
• Bacterial endocarditis
• Cardiac arrhythmias
• Carotid artery stenosis
• Congestive heart failure
• Coronary artery disease

Dermatological conditions

• Acne rosacea
• Atopic eczema
• Dermatitis atopic
• Dermatitis herpetiformis
• Juvenile xanthogranuloma
• Sporotrichosis
• Stevens-Johnson syndrome (erythema multiforme major)
• Toxic epidermal necrolysis (Lyell disease or scalded skin syndrome)

Endocrine disorders

• Hyperparathyroidism
• Myxedema

Eye diseases and conditions

• Phlyctenular keratoconjunctivitis
• Terson syndrome
• Toxic optic neuropathy
• Toxic cataracts (Environmental Exposure to Lead, Drugs including corticosteroids and others)
• Toxic Maculopathies (Plaquenil and other drugs)

Fungal infections

• Candidiasis
• Coccidioidomycosis (Valley Fever)
• Cryptococcosis
• Histoplasmosis

Genetic/hereditary diseases and disorders

• Adrenoleukodystrophy
• Aicardi syndrome
• Alagille syndrome
• Albinism
• Alport syndrome
• Alström syndrome
• Apert syndrome
• Bardet-Biedl syndrome
• Bassen-Kornzweig syndrome
• Bloch-Sulzberger syndrome
• Canavan disease
• Cat eye syndrome
• Cerebrotendinous xanthomatosis
• Chediak-Higashi syndrome
• Cockayne syndrome
• Cohen syndrome
• Cornelia de Lange syndrome
• Cri du chat syndrome
• Crouzon syndrome
• Cystinosis
• De Morsier syndrome
• Delleman syndrome
• Down syndrome
• Edwards syndrome
• Ehlers-Danlos syndrome type 6 (ocular sclerotic)
• Epidermolysis bullosa
• Fraser syndrome
• Friedreich’s ataxia
• Frontonasal dysplasia (medical clefting syndrome)
• Garder syndrome (familial polyposis)
• Gaucher disease
• Gillespie syndrome
• Goltz syndrome
• Gorlin-Goltz (nevoid basal cell carcinoma) syndrome
• Gronblad-Strandberg syndrome (Pseudoxanthoma elasticum)
• Hallermann-Streiff syndrome
• Hallervorden-Spatz syndrome (Pantothenate kinase-associated neurodegeneration)
• Hemochromatosis (primary)
• Hermansky-Pudlak syndrome
• Hirschsprung disease
• Hunter syndrome (mucopolysaccharidosis II)
• Hyperornithinemia
• Ichthyosis (congenital)
• Jeune syndrome
• Klippel-Trénaunay syndrome
• Kniest syndrome
• Laurence-Moon syndrome
• Lecithin-cholesterol-acyltransferase deficiency (Norum disease)
• Lenz microphthalmia syndrome
• Louis-Bar syndrome (Ataxia-telangiectasia)
• Lowe syndrome (oculocerebrorenal syndrome)
• Maffucci syndrome
• Mannosidosis
• Marfan syndrome
• Maroteaux-Lamy syndrome (MPS VI)
• Marshall-Smith syndrome
• McCune-Albright syndrome
• Meckel-Gruber syndrome
• Menkes disease
• Meretoja’s syndrome
• Morquio syndrome type IV A (MPS IV A)
• Mucolipidosis type I (Goldberg syndrome/sialidosis)
• Mucolipidosis type II (Leroy I-cell disease)
• Mucolipidosis type III (pseudo-Hurler polydystrophy syndrome)
• Mucolipidosis type IV
• Multiple endocrine neoplasia type II (Sipple syndrome)
• Myotonic dystrophy
• Nance-Horan syndrome
• Neurofibromatosis I (von Recklinghausen disease)
• Neurofibromatosis type 2
• Nevus of Ota (Oculodermal melanocytosis)
• Niemann-Pick disease type A
• Niemann-Pick disease type B
• Niemann-Pick disease type C
• Niemann-Pick disease type D
• Niemann-Pick disease type E
• Norrie disease
• Oculopharyngeal muscular dystrophy
• Osteogenesis imperfecta type 1
• Osteogenesis imperfecta type 2
• Osteogenesis imperfecta type 3
• Osteogenesis imperfecta type 4
• Pagon syndrome
• Parry-Romberg syndrome
• Peters plus syndrome
• Pierre Robin syndrome
• Prader-Willi syndrome
• Pseudoxanthoma elasticum AD type 1
• Pseudoxanthoma elasticum AD type 2
• Pseudoxanthoma elasticum AR type 1
• Pseudoxanthoma elasticum AR type 2
• Refsum syndrome (heredopathic atactica polyneuritiformis)
• Rendu-Osler-Weber syndrome (hereditary hemorrhagic telangiectasia)
• Rieger syndrome
• Riley-Day syndrome (Familial dysautonomia)
• Rothmund-Thomson syndrome
• Rubinstein-Taybi syndrome
• Sandhoff disease (Gm2 gangliosidosis type II)
• Sanfilippo syndrome (MPS III A-D)
• Scheie syndrome (MPS I S)
• Sjögren-Larsson syndrome
• Sly syndrome (MPS VII)
• Stickler syndrome
• Sturge-Weber syndrome
• Sulfite oxidase deficiency
• Tangier disease
• Tay-Sachs disease (Gm2 gangliosidosis type I)
• Muir-Torre syndrome
• Treacher Collins syndrome
• Tuberous sclerosis (Bourneville disease)
• Turcot syndrome
• Turner syndrome
• Tyrosinemia type II (Richner-Hanhart syndrome)
• Usher syndrome
• Von Hippel-Lindau syndrome
• Waardenburg syndrome
• Walker-Warburg syndrome
• Weill-Marchesani syndrome
• Wildervanck (cervico-oculo-acoustic) syndrome
• Wilson's disease (hepatolenticular degeneration)
• Wolfram syndrome (DIDMOAD)
• Xeroderma pigmentosum
• Zellweger syndrome

Hormonal disorders

• Acromegaly
• Cushing’s syndrome
• Thyroid dysfunction
• Thyrotoxicosis

Inflammatory disorders and conditions

• Ankylosing spondylitis
• Cogan syndrome
• Crohn’s disease
• Dermatomyositis
• Polymyositis
• Giant cell arteritis
• Gout
• Granulomatosis with polyangiitis (GPA) (Wegener’s granulomatosis)
• Hepatitis
• Histiocytosis X (Langerhans cell histiocytosis)
• Juvenile Rheumatoid Arthritis (Juvenile Chronic)
• Kawasaki disease (mucocutaneous lymph node syndrome)
• Pancreatitis (acute)
• Polyarteritis nodosa
• Psoriatic arthritis
• Reiter’s Syndrome (Reactive arthritis)
• Sinusitis Chronic
• Tubulointerstitial nephritis and uveitis (TINU)
• Ulcerative colitis

Injury

• Raised intracranial pressure

Lung condition

• Chronic obstructive pulmonary disease

Mental health diseases and disorders

• Depression
• Schizophrenia
• Substance use disorder (drug & alcohol)

Metabolic and nutritional disorders and deficiencies

• Alkaptonuria
• Fabry disease
• Farber disease
• Fucosidosis
• Galactosemia
• Type 2 diabetes
• Porphyria cutanea tarda (cutaneous hepatic porphyria)
• Pre-diabetes/ IFG/ IGT
• Vitamin A deficiency

Nephrology (kidney) conditions

• Chronic kidney disease
• IgA nephropathy (Berger’s disease)
• Membranoproliferative glomerulonephritis type II
• Oxalosis

Neurological diseases, disorders, and conditions

• Autism spectrum disorder
• Batten disease
• Behr syndrome
• Cerebellar ataxia type I
• Cerebrovascular accident
• Charcot-Marie-Tooth disease
• Dementia (incl. Alzheimer’s disease)
• Migraine
• Moebius syndrome
• Multiple sclerosis
• Nerve diseases and palsies (third, fourth, sixth, seventh)
• Olivopontocerebellar atrophy type III
• Steele-Richardson-Olszewski syndrome (Progressive Supranuclear Palsy)
• Syringomyelia
• Wernicke encephalopathy (Wernicke-Korsakoff syndrome)

Neuromuscular disorder

• Kearns-Sayre syndrome

Parasitic diseases

• Onchocerciasis
• Toxocariasis (Dog Round Worm)
• Toxoplasmosis

Respiratory disease

• Asthma

Sexually transmitted diseases and infections

• Chancroid
• Chlamydia / Adult Inclusion/ TRIC
• Gonorrhea
• Lymphogranuloma venereum
• Syphilis (acquired)

Viral infections

• Cytomegalovirus (congenital)
• Herpes simplex
• Herpes zoster (shingles)
• Human immunodeficiency virus (HIV)
• Influenza
• Measles
• Meningitis
• Rubella
• Varicella (congenital)